Brain Barriers
نویسندگان
چکیده
منابع مشابه
Barriers in the brain: a renaissance?
Barrier mechanisms regulate the exchange of molecules between the brain's internal milieu and the rest of the body. Correct functioning of these mechanisms is critical for normal brain activity, maintenance and development. Dysfunctional brain barrier mechanisms contribute to the pathology of neurological conditions, ranging from trauma to neurodegenerative diseases, and provide obstacles for s...
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Submit Manuscript | http://medcraveonline.com Abbreviations: AD: Alzheimer Disease; Apo-E: ApoLipoprotein-E; BBB: Blood Brain Barrier; Brainpeps: BBB Peptide Database; CNS: Central Nervous System; CSF: CerebroSpinal Fluid; EPIC: Engineered Peptide Compound; HAD: HIVAssociated Dementia; HIFU: High Intensity Focused Ultrasound; HIV: HIV Encephalitis; HIV: Human Immunodeficiency Virus; LPR: Lipopr...
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There is great promise that ongoing advances in the delivery of therapeutics to the central nervous system (CNS) combined with rapidly expanding knowledge of brain tumor patho-biology will provide new, more effective therapies. Brain tumors that form from brain cells, as opposed to those that come from other parts of the body, rarely metastasize outside of the CNS. Instead, the tumor cells inva...
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BACKGROUND Ageing can be simply defined as the process of becoming older, which is genetically determined but also environmentally modulated. With the continuous increase of life expectancy, quality of life during ageing has become one of the biggest challenges of developed countries. The quest for a healthy ageing has led to the extensive study of plant polyphenols with the aim to prevent age-...
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Background/introduction While most brain tumors do not have an intact bloodbrain barrier (BBB), vascular barriers in the tumor and the surrounding intact brain tissue are major challenges for the use of chemotherapy for CNS malignancies. The permeability of brain tumor vessels can be highly heterogeneous, and factors such as high interstitial pressures can prevent agents from reaching an effect...
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ژورنال
عنوان ژورنال: Nature
سال: 1968
ISSN: 0028-0836,1476-4687
DOI: 10.1038/220515c0